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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAMKK2
All Species:
16.97
Human Site:
S136
Identified Species:
41.48
UniProt:
Q96RR4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RR4
NP_006540.3
588
64732
S136
S
P
V
S
S
P
Q
S
S
P
R
L
P
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093436
588
64878
S136
S
P
V
G
S
P
Q
S
S
P
R
L
P
R
R
Dog
Lupus familis
XP_543388
578
63709
S128
S
P
V
G
S
P
Q
S
S
P
R
L
P
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C078
588
64599
S136
S
P
A
S
S
P
Q
S
S
P
R
M
P
R
R
Rat
Rattus norvegicus
O88831
587
64428
S135
S
P
A
S
S
P
Q
S
S
P
R
M
P
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519677
851
91898
D294
G
R
V
R
E
S
A
D
P
R
K
G
R
S
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082316
523
58635
I122
A
S
H
I
S
P
R
I
V
R
R
P
T
I
E
Zebra Danio
Brachydanio rerio
NP_001014361
434
48727
P35
S
S
R
I
A
R
Q
P
T
I
E
S
K
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GN62
617
69630
A141
P
I
P
V
E
S
E
A
M
R
Q
F
I
N
Q
Sea Urchin
Strong. purpuratus
XP_785473
661
73509
H158
N
F
Q
S
W
Q
Q
H
H
E
L
V
R
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
92.1
N.A.
91.8
92.5
N.A.
38.6
N.A.
53.7
52.2
N.A.
N.A.
N.A.
21.5
44.7
Protein Similarity:
100
N.A.
98.8
93.8
N.A.
94.2
94.9
N.A.
50.5
N.A.
67.3
64.1
N.A.
N.A.
N.A.
40
58.4
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
6.6
N.A.
20
20
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
N.A.
33.3
33.3
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
20
0
10
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
20
0
10
0
0
10
10
0
0
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
0
20
0
0
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
20
0
0
0
10
0
10
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
30
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
20
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
10
50
10
0
0
60
0
10
10
50
0
10
50
0
0
% P
% Gln:
0
0
10
0
0
10
70
0
0
0
10
0
0
0
10
% Q
% Arg:
0
10
10
10
0
10
10
0
0
30
60
0
20
60
60
% R
% Ser:
60
20
0
40
60
20
0
50
50
0
0
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% T
% Val:
0
0
40
10
0
0
0
0
10
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _